The Dark Side of EGFP: Defective Polyubiquitination
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چکیده
منابع مشابه
The Dark Side of EGFP: Defective Polyubiquitination
Enhanced Green Fluorescent Protein (EGFP) is the most commonly used live cell reporter despite a number of conflicting reports that it can affect cell physiology. Thus far, the precise mechanism of GFP-associated defects remained unclear. Here we demonstrate that EGFP and EGFP fusion proteins inhibit polyubiquitination, a posttranslational modification that controls a wide variety of cellular p...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2006
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0000054